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TENTATIVE PROGRAM

October 15 (Thu)

19:00-
Welcome reception (Invited speakers only)

October 16 (Fri)

11:30-12:30
Poster Setup
12:30-12:40
Opening remarks
Hirofumi Kai (Kumamoto Univ., Japan)
Shinji Harada (President, Kumamoto Univ., Japan)

Session I : Cystic fibrosis, COPD  Chairperson: Hirofumi Kai

12:40-13:30
Jian-Dong Li (Georgia State Univ., USA)
Negative Feedback Regulation of Inflammation & Novel Anti-Inflammatory Strategy
13:30-14:20
Dieter Gruenert (Univ. of California, San Francisco, USA)
The use of TALENs and CRISPR/Cas9 to Augment SDF-mediated Homology Directed Repair of Inherited Disease Mutations
14:20-15:10
Gergely Lukacs (Mcgill Univ., Canada)
Phenotypic correction of cystic fibrosis by pharmacological chaperones and proteostasis modulators in model systems

Session II : Physical Medicine  Chairperson: Tsuyoshi Shuto

15:30-16:20
Roy Katso (GlaxoSmithKline, UK)
The opportunities of bioelectronics as a treatment paradigm
16:20-17:10
Motohiro Nishida (Nat’l. Inst. for Physiological Sciences, Japan)
Imitation of kinesitherapy by inhibition of TRPC6 channel activities
17:10-18:00
Hirofumi Kai (Kumamoto Univ., Japan)
Beneficial effects and the molecular mechanisms of specific mild electrical stress as physical medicine
18:00-19:00
One-minute poster presentation
19:00-21:00
Poster session & mixer

October 17 (Sat)

Kumamoto University Young Researchers' Session
Chairpersons: Tsukasa Okiyoneda, Hirofumi Jono

9:00-9:30
Tsuyoshi Shuto (Kumamoto Univ., Japan)
Pharmacological and genetic approaches determine protease and oxidative stress as exacerbating factors in a mouse model of obstructive lung diseases
9:30-10:00
Hiroshi Watanabe (Kumamoto Univ., Japan)
Renoprotective effect of albumin-thioredoxin fusion protein by modulating oxidative stress and macrophage migration inhibitory factor against acute kidney injury
10:00-10:30
Hirofumi Jono (Kumamoto Univ., Japan)
Clinical significance of CYLD downregulation in glioblastoma:CYLD, a critical regulator of hypoxia-mediated inflammation in tumors
10:30-11:00
Shingo Ito (Kumamoto Univ., Japan)
Cerebral clearance of amyloid-β peptide across the blood-brain barrier
11:00-12:00
Poster session
12:00-13:00
Poster session(viewing only)& Lunch

Session III : Brain inflammation, Blood-brain barrier
Chairperson: Sumio Ohtsuki

13:00-13:50
Xavier Declèves (INSERM, France)
The blood-brain and neuro-inflammation: mechanisms and consequences
13:50-14:40
Takashi Shichita (Keio Univ., Japan)
The role of innate immunity in ischemic stroke

Session IV : Alport syndrome, Liver fibrosis  Chair: Mary Ann Suico

15:00-15:50
Yasuko Iwakiri (Yale Univ., USA)
Reticulon 4B (Nogo-B): A novel regulator of hepatic inflammation and fibrosis
15:50-16:40
Mary Ann Suico (Kumamoto Univ., Japan)
Podocyte p53 limits the severity of experimental Alport syndrome
16:40
Concluding remarks
Sumio Ohtsuki (Kumamoto Univ., Japan)

October 18 (Sun)

9:00-
Excursion (Aso and Country Gold2015 tour)
(Optional tour, preregistration is required)
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