遺伝子機能応用学研究室

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研究実績
 
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2004年2003年2002年2001年2000年1999年1998年

1999年

  • Hisatsune A, Uto A, Koyanagi T, Chihara T, Miyata T, Basbaum C, Kai H.  [Novel transcription factor MEF is associated with the function of lung epithelial cells] Nippon Yakurigaku Zasshi. 1999;114 Suppl 1:81P-85P.

  • Hosoe H, Kaise T, Ohmori K, Isohama Y, Kai H, Takahama K, Miyata T.  Mucolytic and antitussive effects of erdosteine.
    J Pharm Pharmacol. 1999;51(8):959-66.

  • Nagayama S, Kai H, Okiyoneda T, Horikawa S, Miyata T.  Characterization of CFTR expression in a human pulmonary mucoepidermoid carcinoma cell line, NCI-H292 cells. FEBS Lett. 1999;455(3):215-8.

  • Kai H, Hisatsune A, Chihara T, Uto A, Kokusho A, Miyata T, Basbaum C.  Myeloid ELF-1-like factor up-regulates lysozyme transcription in epithelial cells. J Biol Chem. 1999;274(29):20098-102.

  • Okumura M, Kai H, Shinozawa S, Isohama Y, Miyata T.  Effects of eosinophil granule major basic protein on phosphatidylcholine secretion in rat type II pneumocytes. Am J Physiol. 1999;276(5 Pt 1):L763-8.

  • Tai S, Kai H, Isohama Y, Moriuchi H, Hagino N, Miyata T.  The effect of maimendongtang on airway clearance and secretion.
    Phytother Res. 1999;13(2):124-27.

  • K. Miyake, H. Arima, T. Irie, F. Hirayama and K. Uekama, Enhanced absorption of cyclosporin A by complexation with dimethyl-b-cyclodextrin in bile duct-cannulated and ミnoncannulated rats. Biol. Pharm. Bull., 22 , 66-72, 1999.

  • K. Miyake, T. Irie, H. Arima, F. Hirayama, K. Uekama, M. Hirano, Y. Okamoto, Characterization of itraconazole/2-hydroxypropyl-b-cyclodextrin inclusion complex in aqueous propylene glycol solution. Int. J. Pharm., 179 , 237-245, 1999.

  • N. Ono, F. Hirayama, H. Arima and K. Uekama, Determination of stability constant of b-cyclodextrin complexes using the membrane permeation technique and the permeation behavior of drug-competing agent-b-cyclodextrin ternary systems. Eur. J. Pharm. Sci., 8 , 133-139, 1999.

  • Y. Morimura, Y. Aramaki, H. Arima, T. Sakamoto, L. Insugi and S. Tsuchiya, Resistance of plasmid DNA to DNase by complex formation with cationic liposomes. Drug Delivery system, 14 , 165-169, 1999.

  • Y. Hamano, K. Ito, H. Matsuda, H. Sumioshi, H. Arima, F. Hirayama and K. Uekama, Inhibitory effect of 2-hydroxypropyl-b-cyclodextrin on the foaming generated by the phosphodiester compound of vitamin C and E, EPC-K1. Chem. Pharm. Bull., 47 , 828-832, 1999.

  • F. Hirayama, S. Mieda, Y. Miyamoto, H. Arima and K. Uekama, Heptakis(2,6-di- O -methyl-3- O -acetyl)-b-cyclodextrin: A water-soluble cyclodextrin derivatives with low hemolytic activity. J. Pharm. Sci., 88 , 970-975, 1999.

  • H. Arima, M. Takahashi, Y. Aramaki, T. Sakamoto, K. Yuda, K. Akiyama, T. Goto and S. Tsuchiya, Design of potent phosphorothioate antisense oligonucleotides directed to human interleukin 10 gene product and their evaluation of antisense activity in U937 cells. Pharm. Res., 16 , 1163-1171, 1999.

  • K. Kimura, F. Hirayama, H. Arima and K. Uekama, Solid-state 13C nuclear magnetic resonance spectroscopic study on amorphous solid complexes of tolbutamide with 2-hydroxypropyl-a- and -b-cyclodextrin. Pharm. Res., 16 , 1729-1734, 1999.

  • Y. Aramaki, R. Matsuno, H. Arima and S. Tsuchiya, Macrosialin may not be involved with the regulation of nitric oxide production from mouse peritoneal macrophages stimulated with LPS. Res. Commun. Molec. Pathol. Pharmacol. 104 , 22-30, 1999.

  • H. Matsuda and H. Arima, Cyclodextrins in transdermal and Rectal Delivery. Adv. Drug Deliv. Reviews, 36 , 81-99, 1999.
2000年
1998年


































 

 


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